Facilities, Centers & Institutes

The Duke Center for Human Genetics (CHG) was established in 1996 and uses family histories, sophisticated molecular analyses, and statistical genetics to reveal the genetic origin of a wide array of disorders, including the muscular dystrophies, Alzheimer's disease and cardiovascular diseases.

 

As an academic research organization, the role of the Duke Clinical Research Institute (DCRI) is to provide leadership in the design, execution, and analysis of innovative clinical investigations, and to ensure that these studies are conducted according to the highest methodological and regulatory standards. The DCRI embraces the concept that close integration of clinical, biostatistical, informatics, economics, behavioral, data management, and project management expertise is essential for successful clinical research. DCRI has earned an international reputation as a leader in cardiovascular databases and clinical trials. Its faculty and staff provide intellectual leadership and coordination for more than 100 projects, including clinical trials, outcome studies, and registries, involving more than 200,000 patients across nearly 10,000 clinical research sites in 60 countries.

 

The Duke Clinical Research Unit (DCRU) was one of the first eight sites initiated by the NIH in 1960 for a national DCRU Program to foster clinical research, with an emphasis on translational research from bench to bedside, in the nation's research and teaching hospitals. Its structure built around research teams including clinician investigators, biostatisticians, nutritionists, and behavioral experts, overseen by an advisory committee that reviews the research studies that use the facility. It conducts, on average 53 protocols per year in collaboration with more than 90 investigators.

 

The Institute for Genome Science & Policy (IGSP) includes research programs on Functional Genomics, Computational Sciences and DNA Analysis.