Prior Research Fellows and Trainees in Hematology and Medical Oncology

Research Fellows in Hematology and Medical Oncology

2006-2008

Nicole Whitlatch, MD

Research Project:

1. NIH-funded clinical trial assessing the incidence of thromboembolic events in patients with Heparin-PF4 antibodies after cardiac bypass

2. Identifying patients with HIT who are at high risk for thromboembolic events, using clinical algorithms and genomics/proteomics

Representative Publications:

1. Perry SL, Whitlatch NL, Ortel TL. Clinical management and outcomes of patients with heparin/platelet factor 4 antibodies: retrospective review at a single center. Blood, 2006 (abstract accepted for poster presentation).

2005-2007

Veshana Ramiah, MD

Research Projects:

1. Genomic analysis of thrombotic risk in patients with malignancy

2. Gene expression strategies to identify patients at high risk for recurrent thrombosis

Awards:

Recipent, ASH Clinical Research Training Institute, 2006.

Representative Publications:

Potti A, Ramiah V, Ortel TL. Thrombophilia and Thrombosis in TTP. Semin.Thromb.Hemostasis, (in review).

Current Position:

Instructor, Department of Medicine, Division of Medical Oncology, Duke University Medical Center, Durham, NC

2004-2006

Elizabeth Krakow, MD

Research Project:

Incidence of anti-heparin/platelet factor 4 antibodies and heparin-induced

thrombocytopenia following cardiopulmonary bypass procedures.

Awards:

Recipient, Primer Award (supported by Pfizer), 2004-2005.

Current Position:

Clinical Scholar, Division of Hematology, Department of Medicine, McMaster University and Hamilton Health Sciences

2004-2006

Anil Potti, MBBS

Research Projects:

1. Genomic analysis of thrombotic risk in patients with antiphospholipid syndrome.

Representative Publications:

1. Potti A, Rusconi CP, Sullenger BA, Ortel TL. Regulatable aptamers in medicine:

focus on antithrombotic strategies. Expert Opin.Biol.Ther., 2004; 4: 1641-1647.

2. Potti A, Danielson B, Badreddine R, Ortel T. Potassium homeostasis in patients

receiving prophylactic dose enoxaparin therapy. J.Thromb.Haemost., 2004; 2: 1208-1209.

Awards:

Recipient, ASH Clinical Research Training Institute, 2004.

Current Position:

Faculty, Associate Professor in the Department of Medical Oncology, Duke University Medical Center, Durham, NC.

2002-2004

Zöe Larned, MD

Research Projects:

1. Hypercoagulability associated with hormonal therapy in patients with breast cancer.

Representative Publications:

1. Larned ZL, O’Shea SI, Ortel TL. Heparin-Induced Thrombocytopenia: Clinical Presentations and Therapeutic Management. Clin. Adv. in Hematology & Oncology, 2003; 1: 356-364.

Current Position:

Ochsner Clinic, New Orleans, LA

2001-2003

Stephanie Perry, MD, PharmD

Research Projects:

1. Monitoring anticoagulation in patients with lupus anticoagulants.

2. Pharmacokinetic analysis of low-molecular weight heparin in patients with

    end-stage renal disease.

Representative Publications:

1. Perry SL, O’Shea SI, Ortel TL. Management of lepirudin therapy for a patient with

    antiphospholipid antibody syndrome using the whole blood ecarin clot time and aPTT.

    Blood Coag.Fibrinol., 2003; 14: 601-604.

2. Lukes AS, Perry S, Ortel TL. von Willebrand’s disease diagnosed after menorrhagia

    worsened from levonorgestrel intrauterine system. Obstet.Gynecol., 2005; 105: 1223-1226.

Awards:

Recipient, Mentored Clinical Research Scholars Program (K12 award), 2003-present.

Current Position:

Assistant Professor, Brain Tumor Center, Duke University Medical Center, Durham, NC.

2000-2002

Susan O’Shea, MBBS

Research Projects:

1. Hypercoagulable states and antithrombotic strategies in hemodialysis-dependent patients.

2. Expert-system based management strategy for patient self-management of oral anticoagulant therapy.

Representative Publications:

1. O’Shea SI, Ortel TL, Kovalik EC. Alternative methods of anticoagulation in dialysis-dependent patients with heparin induced thrombocytopenia. Semin. Dialysis, 2003; 16: 61-67.

2. O’Shea SI, Lawson JH, Reddan D, Ortel TL. Hypercoagulable states and antithrombotic strategies in patients with recurrent vascular access thrombosis. J. Vasc. Surg., 2003; 38:541-548.

Awards:

Recipient, ASH Scholar Award, 2002-2004.

Current Position:

Acting Consultant Haematologist, Cork University Hospital, Cork, Ireland.